Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18759031 | 0.90 | CA14 (0.42) | CA14CA12CA1CA9MLYCD | |
| SCHEMBL25969918 | 0.89 | CA14 (0.54) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL8285770 | 0.86 | CA14 (0.51) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL25489016 | 0.86 | CA14 (0.51) | CA14CA12CA1HDAC1HDAC2 | |
| SCHEMBL18769164 | 0.85 | CA14 (0.46) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL20365669 | 0.84 | MLYCD (0.44) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL14755630 | 0.84 | CA14 (0.54) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL8021973 | 0.84 | CA14 (0.54) | CA14MMP1MMP2MMP3MMP8 | |
| SCHEMBL23857521 | 0.83 | CA14 (0.45) | CA14MLYCDHDAC1HDAC2HDAC3 | |
| SCHEMBL3024648 | 0.83 | CA14 (0.53) | CA14MMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066797-A1 | TRINUCLEOTIDE MRNA CAP ANALOGS | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |