SCHEMBL187595

SCHEMBL187595

CN(C)c1ccc(N(C)C)c2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.74
ALDH1A1 P00352 7/20 0.74
L3MBTL1 Q9Y468 5/20 0.74
TDP1 Q9NUW8 5/20 0.74
MAPK1 P28482 5/20 0.74
LMNA P02545 3/20 0.74
EGFR P00533 2/20 0.74
NSD2 O96028 1/20 0.74
MEN1 O00255 5/20 0.59
KMT2A Q03164 5/20 0.59
RAB9A P51151 5/20 0.59
NPSR1 Q6W5P4 2/20 0.59
PTK2B Q14289 1/20 0.59
MALT1 Q9UDY8 1/20 0.48
CDC25B P30305 3/20 0.48
SMN1; SMN2 Q16637 6/20 0.47
KDM4E B2RXH2 4/20 0.47
HTT P42858 2/20 0.47
HIF1A Q16665 2/20 0.47
USP2 O75604 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31171427 1.00 MAPT (0.74) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL11308787 0.87 MAPT (0.59) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL17228665 0.87 MAPT (0.59) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL187706 0.85 L3MBTL1 (1.00) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL2362908 0.85 MAPT (0.85) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL16997427 0.84 ALDH1A1 (0.56) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL30231841 0.83 ALDH1A1 (0.54) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL16144956 0.83 ALDH1A1 (0.54) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL18984670 0.83 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1TDP1MAPK1
SCHEMBL18984785 0.82 MAPT (0.88) MAPTALDH1A1L3MBTL1TDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3421511-B1 AROMATIC VINYL-DIENE COPOLYMER, METHOD FOR PRODUCING AROMATIC VINYL-DIENE COPOLYMER, AND RUBBER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2025-08-27 EP disclosed
US-12110354-B2 Production method for aromatic vinyl-diene copolymer and production method for rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2024-10-08 US disclosed
US-11518835-B2 Conveyor belt rubber composition, method for producing conveyor belt rubber composition, conveyor belt, and belt conveyor THE YOKOHAMA RUBBER CO., LTD. (JP) 2022-12-06 US disclosed
US-11498993-B2 Conveyor belt rubber composition, method for producing conveyor belt rubber composition, conveyor belt, and belt conveyor THE YOKOHAMA RUBBER CO., LTD. (JP) 2022-11-15 US disclosed
US-20210246246-A1 PRODUCTION METHOD FOR AROMATIC VINYL-DIENE COPOLYMER AND PRODUCTION METHOD FOR RUBBER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2021-08-12 US disclosed
US-11008445-B2 Aromatic vinyl-diene copolymer, method for producing aromatic vinyl-diene copolymer, and rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2021-05-18 US disclosed
US-11001654-B2 Diene polymer, method for producing diene polymer, and rubber composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2021-05-11 US disclosed
EP-3348588-B1 DIENE POLYMER, METHOD FOR PRODUCING DIENE POLYMER, AND RUBBER COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2020-07-29 EP disclosed
US-10263308-B2 Solar flow battery CORNELL UNIVERSITY (US) 2019-04-16 US disclosed
US-20190023880-A1 AROMATIC VINYL-DIENE COPOLYMER, METHOD FOR PRODUCING AROMATIC VINYL-DIENE COPOLYMER, AND RUBBER COMPOSITION THE YOKOHAMA RUBBER CO., LTD. (JP) 2019-01-24 US disclosed
EP-1719799-A1 Run flat tire Sumitomo Rubber Industries, Ltd. (JP) 2006-11-08 EP disclosed
US-20060247365-A1 Side reinforcing layer in which low exothermic property and high hardness are compatible and durability is improved; carbon black of specified absorption, natural ore such as sericite, a conjugated diene polymer modified with alkoxysilyl and primary amine groups, and coupled with bifunctional monomers SUMITOMO RUBBER INDUSTRIES, LTD. 2006-11-02 US disclosed
EP-0992537-B1 Oil extended rubber and rubber composition JSR CORP (JP) 2004-12-29 EP disclosed
US-20040254301-A1 Conjugated diolefin (co)polymer rubber, process for producing (co)polymer rubber, rubber composition, composite, and tire JSR CORPORATION (JP) 2004-12-16 US disclosed
EP-1457501-A1 CONJUGATED DIOLEFIN POLYMER RUBBER PROCESS FOR PRODUCING POLYMER RUBBER RUBBER COMPOSITION COMPOSITE AND TIRE JSR Corporation (JP) 2004-09-15 EP disclosed
EP-0924227-B1 Conjugated diolefin-based copolymer rubber and composition thereof JSR CORP (JP) 2004-03-10 EP disclosed
US-6362272-B1 CONJUGATED DIOLEFIN AND AROMATIC VINYL COPOLYMER JSR CORPORATION (JP) 2002-03-26 US disclosed
US-6191234-B1 CONJUGATED DIENE-AROMATIC VINYL COPOLYMER OBTAINED BY MODIFYING POLYMER WITH A AMINO GROUP IS USED TO IMPROVE WET SKID RESISTANCE, WEAR RESISTANCE OF AUTOMOBILE TIRE TREAD JSR CORPORATION (JP) 2001-02-20 US disclosed
EP-0992537-A1 Oil extended rubber and rubber composition JSR Corporation (JP) 2000-04-12 EP disclosed
EP-0924227-A1 Conjugated diolefin-based copolymer rubber and composition thereof JSR Corporation (JP) 1999-06-23 EP disclosed