SCHEMBL18759587

SCHEMBL18759587

CC1(OCc2ccccc2)CCC(OCc2ccccc2)CC1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 2/20 0.60
OPRL1 P41146 2/20 0.60
DPP4 P27487 1/20 0.56
SIGMAR1 Q99720 2/20 0.47
CARM1 Q86X55 3/20 0.47
PRMT6 Q96LA8 3/20 0.47
PRMT8 Q9NR22 2/20 0.47
TMEM97 Q5BJF2 1/20 0.47
HRH3 Q9Y5N1 1/20 0.47
CTSL P07711 1/20 0.43
CTSB P07858 1/20 0.43
CTSK P43235 1/20 0.43
BCHE P06276 1/20 0.40
EPHX2 P34913 1/20 0.40
PRMT3 O60678 1/20 0.38
PSEN1 P49768 1/20 0.38
PSEN2 P49810 1/20 0.38
APH1B Q8WW43 1/20 0.38
NCSTN Q92542 1/20 0.38
APH1A Q96BI3 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7076809 0.82 TSHR (0.46) OPRM1OPRL1BCHE
SCHEMBL22488577 0.82 OPRM1 (0.61) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL27619185 0.79 OPRL1 (0.39) OPRM1OPRL1DPP4
SCHEMBL1551250 0.79 OPRM1 (0.61) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL355570 0.79 OPRM1 (0.56) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL3660170 0.79 OPRM1 (0.56) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL6469380 0.78 OPRM1 (0.59) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL651048 0.78 OPRM1 (0.57) OPRM1OPRL1DPP4SIGMAR1CARM1
SCHEMBL19388482 0.78 OPRM1 (0.60) OPRM1OPRL1DPP4SIGMAR1CARM1
Methyl Alcohol SCHEMBL10438266 0.78 OPRM1 (0.55) OPRM1OPRL1DPP4SIGMAR1CARM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1472293-B1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2017-04-26 EP disclosed