Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.60 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.60 |
| ▸ | DPP4 | P27487 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.50 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.47 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.47 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11945827 | 0.90 | OPRM1 (0.54) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL21072321 | 0.85 | OPRM1 (0.56) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL1551250 | 0.83 | OPRM1 (0.61) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL6469380 | 0.82 | OPRM1 (0.59) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL3830852 | 0.81 | CTSL (0.49) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL15797812 | 0.81 | OPRM1 (0.54) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL22111662 | 0.80 | OPRM1 (0.48) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL22488577 | 0.79 | OPRM1 (0.61) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL26906146 | 0.79 | OPRM1 (0.57) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL355570 | 0.79 | OPRM1 (0.56) | OPRM1OPRL1DPP4SIGMAR1CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3504176-B1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2020-06-17 | — | — | EP | disclosed |
| WO-2018037254-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2018-03-01 | — | — | WO | disclosed |
| WO-2018037086-A1 | DIFLUORINATED COMPOUNDS AS DEPIGMENTING OR LIGHTENING AGENTS | TFCHEM (FR) | 2018-03-01 | — | — | WO | disclosed |
| US-9770439-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-26 | — | — | US | disclosed |