Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FUT5 | Q11128 | 1/20 | 0.51 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 7/20 | 0.48 |
| ▸ | NT5E | P21589 | 1/20 | 0.48 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.47 |
| ▸ | DCPS | Q96C86 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.43 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18763919 | 0.94 | FUT5 (0.57) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763551 | 0.93 | FUT5 (0.53) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763554 | 0.92 | FUT5 (0.48) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18769520 | 0.92 | FUT5 (0.48) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763550 | 0.90 | TGM2 (0.50) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763608 | 0.88 | FUT5 (0.56) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763251 | 0.88 | FUT5 (0.57) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763244 | 0.87 | FUT5 (0.56) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18769124 | 0.87 | TGM2 (0.63) | FUT5TGM2KRASNT5EP2RY2 | |
| SCHEMBL18763259 | 0.86 | FUT5 (0.55) | FUT5TGM2KRASNT5EP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066793-A1 | MRNA CAP ANALOGS AND METHODS OF MRNA CAPPING | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| WO-2017066789-A1 | MRNA CAP ANALOGS WITH MODIFIED SUGAR | MODERNATX, INC. (US) | 2017-04-20 | — | — | WO | disclosed |