Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RORC | P51449 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.48 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.48 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.48 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | PHGDH | O43175 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL195876 | 0.91 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1RORC | |
| SCHEMBL29505642 | 0.91 | KMT2A (0.63) | KMT2AMEN1RAB9ANPC1RORC | |
| SCHEMBL29505853 | 0.77 | MAPT (0.51) | KMT2ARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL18764684 | 0.77 | MAPT (0.51) | KMT2ARAB9ANPC1ALDH1A1MAPT | |
| SCHEMBL11754251 | 0.77 | KMT2A (0.59) | KMT2AMEN1RAB9ANPC1PDK1 | |
| SCHEMBL6377318 | 0.75 | KMT2A (0.71) | KMT2AMEN1RAB9ANPC1TDP1 | |
| SCHEMBL18256222 | 0.74 | ALDH1A1 (0.56) | KMT2AMEN1RAB9ANPC1CTDSP1 | |
| SCHEMBL22807394 | 0.74 | ALDH1A1 (0.71) | KMT2ARAB9ANPC1KCNMA1ALDH1A1 | |
| SCHEMBL733777 | 0.74 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1PDK1 | |
| SCHEMBL5797988 | 0.74 | KMT2A (0.69) | KMT2AMEN1RAB9ANPC1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365339-A1 | NOVEL FERROPORTIN INHIBITORS | Vifor (International) AG (CH) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017068090-A1 | NOVEL FERROPORTIN INHIBITORS | VIFOR (INTERNATIONAL) AG (CH) | 2017-04-27 | — | — | WO | disclosed |