Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18766901 | 0.82 | MAPT (0.46) | MEN1KMT2AMAPTNPC1GAA | |
| SCHEMBL18766903 | 0.76 | KMT2A (0.43) | MEN1KMT2AMAPTNPC1GAA | |
| SCHEMBL18766904 | 0.71 | KDM4E (0.44) | MEN1KMT2AMAPTNPC1KDM4E | |
| SCHEMBL11094660 | 0.71 | MAPT (0.54) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL18768348 | 0.70 | MEN1 (0.67) | MEN1KMT2AHTR1ASLC6A4 | |
| SCHEMBL1965727 | 0.69 | CHRM2 (0.60) | MEN1KMT2ANPC1KDM4EALDH1A1 | |
| Ethylene SCHEMBL11094451 | 0.69 | MAPT (0.52) | MEN1KMT2AMAPTGAAL3MBTL1 | |
| SCHEMBL8422440 | 0.68 | SLC6A2 (0.41) | MEN1KMT2AMAPTLMNASLC6A4 | |
| SCHEMBL25525962 | 0.66 | TAAR1 (0.50) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL8279674 | 0.66 | CHRM2 (0.68) | MEN1KMT2AGAASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |