Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CKS1B | P61024 | 1/20 | 0.42 |
| ▸ | SKP1 | P63208 | 1/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29725632 | 0.83 | MEN1 (0.57) | MAPTMEN1KMT2ADRD2ALDH1A1 | |
| SCHEMBL18766902 | 0.82 | MEN1 (0.46) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL18768210 | 0.82 | ACACB (0.47) | MAPTMEN1KMT2ASMN1; SMN2DRD2 | |
| SCHEMBL18766905 | 0.82 | KMT2A (0.54) | MAPTMEN1KMT2ADRD2TGFBR1 | |
| SCHEMBL18766903 | 0.81 | KMT2A (0.43) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL29725623 | 0.72 | ACHE (0.61) | MEN1KMT2ASMN1; SMN2DRD2 | |
| SCHEMBL3418637 | 0.72 | ALDH1A1 (0.62) | MAPTMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL32665269 | 0.71 | CKS1B (0.55) | MAPTKMT2ADRD2ACACBCKS1B | |
| SCHEMBL3052457 | 0.71 | HDAC3 (0.59) | DRD2CKS1BSKP1SKP2 | |
| SCHEMBL29725612 | 0.70 | MAPT (0.63) | MAPTSMN1; SMN2DRD2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |