Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17034884 | 0.81 | NAPRT (0.43) | NAPRTGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL18334563 | 0.79 | PTGS2 (0.44) | GAASMN1; SMN2MAPTKDM4ERAB9A | |
| SCHEMBL17035394 | 0.79 | PTGS2 (0.44) | GAASMN1; SMN2MAPTKDM4ERAB9A | |
| SCHEMBL18768143 | 0.79 | PTGS2 (0.44) | GAASMN1; SMN2MAPTKDM4ERAB9A | |
| SCHEMBL18768138 | 0.76 | ESR1 (0.43) | NAPRTGAASMN1; SMN2MAPTKDM4E | |
| SCHEMBL18768144 | 0.76 | MAPT (0.42) | GAASMN1; SMN2MAPTKDM4ERAB9A | |
| SCHEMBL24192360 | 0.74 | NPC1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL19281410 | 0.74 | NPC1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL24192005 | 0.74 | NPC1 (0.54) | SMN1; SMN2MAPTRAB9AALDH1A1NPC1 | |
| SCHEMBL18768225 | 0.73 | NAPRT (0.43) | NAPRTGAASMN1; SMN2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170107207-A1 | AMINOPYRAZOLONE DERIVATIVE | ATAD5, ATP1A1, TIPRL | NAPRT 3425/4885GAA 2530/4885SMN1; SMN2 4135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.