Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 4/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768567 | 0.93 | MDM2 (0.49) | — | |
| SCHEMBL18768551 | 0.92 | ATM (0.48) | ACHE | |
| SCHEMBL18768425 | 0.90 | MEN1 (0.51) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL18768615 | 0.90 | ATM (0.49) | ACHESLC6A2SLC6A4 | |
| SCHEMBL18768405 | 0.89 | MEN1 (0.52) | ACHE | |
| SCHEMBL18768411 | 0.88 | LMNA (0.48) | — | |
| SCHEMBL18768434 | 0.88 | — | — | |
| SCHEMBL18768424 | 0.87 | AKR1C3 (0.49) | ACHESLC6A2SLC6A4BCHEMAOA | |
| SCHEMBL18768427 | 0.81 | — | — | |
| SCHEMBL18768355 | 0.81 | MAOB (0.64) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |