Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.48 |
| ▸ | ACHE | P22303 | 3/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18768571 | 0.93 | AKR1C3 (0.47) | AKR1C3AR | |
| SCHEMBL18768429 | 0.93 | KDM4E (0.47) | AKR1C3SLC6A2SLC6A4ARSIGMAR1 | |
| SCHEMBL18768423 | 0.93 | AKR1C3 (0.46) | AKR1C3SLC6A4ARACHE | |
| SCHEMBL18768624 | 0.91 | DRD3 (0.49) | ACHEBCHEMAOAMAOBBACE1 | |
| SCHEMBL18768565 | 0.91 | DRD2 (0.46) | AKR1C3SLC6A2SLC6A4ARACHE | |
| SCHEMBL18768569 | 0.89 | OPRM1 (0.49) | ACHESIGMAR1 | |
| SCHEMBL18768363 | 0.89 | AR (0.48) | AKR1C3ARACHE | |
| SCHEMBL18768357 | 0.87 | ACHE (0.52) | SLC6A2SLC6A4ACHEBCHEMAOA | |
| SCHEMBL18768360 | 0.87 | AKR1C3 (0.46) | AKR1C3ARACHE | |
| SCHEMBL18768568 | 0.85 | ACHE (0.45) | AKR1C3ARACHEBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066705-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE AGAINST STRESS GRANULES | AQUINNAH PHARMACEUTICALS, INC. (US) | 2017-04-20 | — | — | WO | disclosed |