Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 12/20 | 1.00 |
| ▸ | HSD11B2 | P80365 | 11/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 1.00 |
| ▸ | HMGB1 | P09429 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | CES2 | O00748 | 3/20 | 0.65 |
| ▸ | CES1 | P23141 | 3/20 | 0.65 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.65 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | MAPT | P10636 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.63 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.63 |
| ▸ | PRKCH | P24723 | 1/20 | 0.63 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isoglycirrhizinate SCHEMBL10065729 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL14551740 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL14733579 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL21424347 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL24626512 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL14514293 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL23309804 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL23747025 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL22200125 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 | |
| Glycyrrhizin SCHEMBL14514292 | 1.00 | HSD11B1 (1.00) | HSD11B1HSD11B2SLCO1B3SLCO1B1HMGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017066787-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF MAKING AND USING THE SAME | LEBEDYEVA IRYNA O (US) | 2017-04-20 | — | — | WO | disclosed |