Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 7/20 | 0.67 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.64 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.64 |
| ▸ | F2 | P00734 | 1/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.60 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Substance P SCHEMBL19057679 | 1.00 | OPRD1 (0.67) | OPRD1NMUR2NMUR1F2OPRM1 | |
| Substance P SCHEMBL17887651 | 1.00 | OPRD1 (0.67) | OPRD1NMUR2NMUR1F2OPRM1 | |
| Substance P SCHEMBL29831869 | 1.00 | OPRD1 (0.67) | OPRD1NMUR2NMUR1F2OPRM1 | |
| Substance P SCHEMBL1116347 | 1.00 | OPRD1 (0.67) | OPRD1NMUR2NMUR1F2OPRM1 | |
| SCHEMBL31332027 | 0.97 | OPRD1 (0.71) | OPRD1NMUR2NMUR1OPRM1OPRK1 | |
| SCHEMBL30342262 | 0.97 | OPRD1 (0.71) | OPRD1NMUR2NMUR1OPRM1OPRK1 | |
| SCHEMBL30013957 | 0.97 | OPRD1 (0.63) | OPRD1NMUR2NMUR1F2 | |
| SCHEMBL29369748 | 0.93 | OPRD1 (0.59) | OPRD1NMUR2NMUR1F2 | |
| SCHEMBL29498256 | 0.93 | OPRD1 (0.67) | OPRD1NMUR2NMUR1F2OPRM1 | |
| SCHEMBL8459620 | 0.92 | OPRM1 (0.61) | OPRD1NMUR2NMUR1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170105926-A1 | COMPOSITION COMPRISING EXTRACT OF ALPINE WORMWOOD | AMOREPACIFIC CORPORATION (KR) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170105926-A1 | COMPOSITION COMPRISING EXTRACT OF ALPINE WORMWOOD | EDNRA, ECE1, EDNRB | OPRD1 1216/4885NMUR2 2045/4885NMUR1 764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.