Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL891299 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL19058567 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL18547997 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL10193093 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL18547814 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL24540457 | 1.00 | TRPM8 (0.48) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL2628727 | 0.89 | TRPM8 (0.51) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL13465385 | 0.88 | TAAR1 (0.60) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL24540270 | 0.88 | TAAR1 (0.60) | TRPM8EPHX1TAAR1MEN1NTSR1 | |
| SCHEMBL2628665 | 0.88 | TAAR1 (0.60) | TRPM8EPHX1TAAR1MEN1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3365324-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | The Procter and Gamble Company (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070418-A1 | SYNTHESIS OF CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY (US) | 2017-04-27 | — | — | WO | disclosed |