Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628652 | 1.00 | TAAR1 (0.60) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL24540270 | 1.00 | TAAR1 (0.60) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL2628665 | 1.00 | TAAR1 (0.60) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL2628727 | 0.91 | TRPM8 (0.51) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL2628626 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL2628627 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL29112425 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL18786371 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL24540582 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 | |
| SCHEMBL2628609 | 0.89 | TRPM8 (0.52) | TAAR1TRPM8EPHX1MEN1NTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200138764-A1 | METHODS AND DEVICES FOR ACTIVATING ADIPOSE TISSUE | THE PROCTER & GAMBLE COMPANY | 2020-05-07 | — | — | US | disclosed |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | PROCTER & GAMBLE (US) | 2017-03-02 | — | — | US | disclosed |
| EP-2510925-A2 | Small-Molecule modulators of TRP-P8 activity | DENDREON CORPORATION (US) | 2012-10-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200138764-A1 | METHODS AND DEVICES FOR ACTIVATING ADIPOSE TISSUE | LRBA, FABP4, LIPE | TAAR1 3380/4885TRPM8 138/4885EPHX1 1278/4885 |
| US-20170057911-A1 | SYNTHESIS OF ARYL CYCLOHEXANE CARBOXAMIDE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, ACMSD, SRM | TAAR1 110/4885TRPM8 376/4885EPHX1 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.