Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.31 |
| ▸ | PGR | P06401 | 3/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18792145 | 0.76 | CYP1A2 (0.45) | CYP1A2ADRB2L3MBTL1NR3C2NR3C1 | |
| SCHEMBL18792143 | 0.75 | ADRB2 (0.39) | CYP1A2ADRB2L3MBTL1NR3C2NR3C1 | |
| SCHEMBL18769849 | 0.73 | ADRB2 (0.56) | ADRB2 | |
| SCHEMBL7832116 | 0.70 | CYP1A2 (0.54) | CYP1A2DAO | |
| SCHEMBL18769904 | 0.70 | ADRB2 (0.48) | ADRB2 | |
| SCHEMBL18769831 | 0.70 | ADRB2 (0.58) | ADRB2 | |
| SCHEMBL11780688 | 0.69 | IDO1 (0.46) | CYP1A2ADRB2L3MBTL1 | |
| SCHEMBL12061479 | 0.69 | CYP1A2 (0.56) | CYP1A2 | |
| SCHEMBL18769901 | 0.69 | ADRB2 (0.50) | CYP1A2ADRB2L3MBTL1 | |
| SCHEMBL18769851 | 0.68 | SIGMAR1 (0.46) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3371181-A1 | COMPOSITIONS AND METHODS OF REGULATING CANCER RELATED DISORDERS AND DISEASES | Onco Therapies LLC (US) | 2018-09-12 | — | — | EP | disclosed |
| WO-2017070052-A1 | COMPOSITIONS AND METHODS OF REGULATING CANCER RELATED DISORDERS AND DISEASES | ONCO THERAPIES LLC (US) | 2017-04-27 | — | — | WO | disclosed |