SCHEMBL18770547

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL22587290	0.89	CYP1A2 (0.50)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL28576167	0.89	L3MBTL1 (0.49)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL1406699	0.89	CYP1A2 (0.53)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL28022588	0.86	CYP1A2 (0.50)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL7369566	0.83	CYP1A2 (0.41)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL4800391	0.83	KMT2A (0.50)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL11614940	0.83	KMT2A (0.50)	CYP1A2KMT2APOLBL3MBTL1GAA
	SCHEMBL11121706	0.82	TSHR (0.50)	KMT2AL3MBTL1GAAMGAMSI
	SCHEMBL3819477	0.82	CYP1A2 (0.50)	CYP1A2KMT2APOLBGAANR1I2
	SCHEMBL3826148	0.82	CYP1A2 (0.50)	CYP1A2KMT2APOLBGAANR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.