Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 3/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20854287 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL29489674 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL22636108 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL162434 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL202556 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL29220481 | 0.81 | CA1 (0.31) | CA1CA2KIF11DPP4DPP8 | |
| SCHEMBL574079 | 0.81 | ALDH1A1 (0.34) | CA1CA2KIF11 | |
| SCHEMBL23376687 | 0.79 | CA1 (0.30) | CA1CA2 | |
| SCHEMBL5372673 | 0.78 | CA1 (0.37) | CA1CA2KIF11 | |
| SCHEMBL11333891 | 0.78 | CA1 (0.37) | CA1CA2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3364958-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | Navitor Pharmaceuticals, Inc. (US) | 2018-08-29 | — | — | EP | disclosed |
| WO-2017070518-A1 | MODULATORS OF SESTRIN-GATOR2 INTERACTION AND USES THEREOF | NAVITOR PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | WO | disclosed |