6-Hydroxycoumarin

6-Hydroxycoumarin

SCHEMBL187709

O=c1ccc2cc(O)ccc2o1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 8/20 1.00
CA9 Q16790 8/20 1.00
MCL1 Q07820 4/20 1.00
ALDH1A1 P00352 4/20 0.74
CA1 P00915 4/20 0.74
HPGD P15428 3/20 0.74
HSD17B10 Q99714 3/20 0.74
TDP1 Q9NUW8 3/20 0.74
KDM4E B2RXH2 2/20 0.74
GLA P06280 2/20 0.74
GAA P10253 2/20 0.74
AKR1B1 P15121 2/20 0.74
CASP1 P29466 2/20 0.74
CASP7 P55210 2/20 0.74
ERAP1 Q9NZ08 2/20 0.74
MEN1 O00255 2/20 0.74
KMT2A Q03164 2/20 0.74
LMNA P02545 3/20 0.62
CYP1A2 P05177 2/20 0.62
CYP3A4 P08684 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Hydroxycoumarin SCHEMBL30640534 1.00 CA12 (1.00) CA12CA9MCL1ALDH1A1CA1
6-Hydroxycoumarin SCHEMBL15157475 0.91 CA12 (0.83) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL11137587 0.85 CA9 (1.00) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL29624448 0.85 CA9 (1.00) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL29396070 0.85 CA9 (1.00) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL22018 0.85 CA9 (1.00) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL307982 0.83 CA9 (0.96) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL27700116 0.83 CA9 (0.96) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL2767044 0.83 CA9 (0.96) CA12CA9MCL1ALDH1A1CA1
Umbelliferone SCHEMBL27915972 0.83 CA9 (0.96) CA12CA9MCL1ALDH1A1CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 423 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304727-A1 PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, COUMARIN-BASED SENSITIZERS AND AMINE ADDITIVES IGM GROUP B.V. (NL) 2025-10-02 US claimed
EP-4519376-A1 PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, COUMARIN-BASED SENSITIZERS AND AMINE ADDITIVES IGM Group B.V. (NL) 2025-03-12 EP claimed
CN-118325486-A Bio-based UV (ultraviolet) curing acrylate pressure-sensitive adhesive and preparation method thereof 青岛德聚胶接技术有限公司 2024-07-12 CN claimed
CN-117721161-A Biological-based multifunctional anti-aging auxiliary agent, and preparation method and application thereof 四川大学 2024-03-19 CN claimed
CN-117461639-A Application of coumarin compound in preventing and treating citrus yellow dragon disease or killing psyllids 赣南师范大学 2024-01-30 CN claimed
EP-4303307-A1 METHOD FOR PRODUCING FLAVOURS USING O-METHYLTRANSFERASE FROM PLEUROTUS Justus-Liebig-Universität Gießen Rechtsabteilung (DE) 2024-01-10 EP claimed
CN-114702668-B UV self-poly main chain type benzoxazine resin and preparation method thereof 镇江利德尔复合材料有限公司 2023-11-14 CN claimed
WO-2023214013-A1 PHOTOINITIATOR PACKAGE COMPRISING PHOSPHINE OXIDE PHOTOINITIATORS, COUMARIN-BASED SENSITIZERS AND AMINE ADDITIVES IGM GROUP B. V. (NL) 2023-11-09 WO claimed
CN-114805794-B Application of compound in improving molecular weight of nylon 金发科技股份有限公司 2023-08-29 CN claimed
CN-115851110-B Preparation method of light response long-acting super-lubricating anti-fouling paint based on coumarin 浙江大学 2023-08-15 CN claimed
CN-106946827-B Preparation method of 6-hydroxycoumarin 常州佳德医药科技有限公司 2020-01-21 CN claimed
CN-108598533-A Cyclization cross-linked polyimide proton exchange membrane based on cumarin and preparation method thereof 同济大学 2018-09-28 CN claimed
CN-106946827-A The preparation method of 6 Hydroxycoumarins 常州佳德医药科技有限公司 2017-07-14 CN claimed
WO-2015101609-A1 METHOD FOR TREATING RENAL DISORDERS STICHTING KATHOLIEKE UNIVERSITEIT (NL) 2015-07-09 WO claimed
CN-104277226-A Siloxane polymers with a central polysiloxane polymer block with organofunctional radicals each having at least two bivalent groups selected from urea and/or carbamate groups and at least one UV/Vis chromophore as radical EVONIK INDUSTRIES AG 2015-01-14 CN claimed
EP-2821430-A1 Siloxane polymers with central polysiloxane polymer block with organofunctional residues, each comprising at least two bivalent groups selected from urea and/or carbamate groups and at least one UV/Vis chromophore as residue Evonik Industries AG (DE) 2015-01-07 EP claimed
US-20050040396-A1 Light emitter for a display UNIVERSITY OF HULL (GB) 2005-02-24 US claimed
US-6830831-B2 For use in backlights, electronic apparatus and security viewers UNIVERSITY OF HULL (GB) 2004-12-14 US claimed
US-20030099862-A1 Light emitter for a display HULL, UNIVERSITY OF (GB) 2003-05-29 US claimed
US-20030027017-A1 Light emitter for a display HULL, UNIVERSITY OF (GB) 2003-02-06 US claimed