Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 4/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.36 |
| ▸ | SMO | Q99835 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTR5A | P47898 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1872975 | 0.91 | QPCT (0.38) | SLC2A1SMO | |
| Trifluoroacetic Acid SCHEMBL3052842 | 0.91 | DRD2 (0.44) | DRD2SLC2A1MTNR1AMTNR1BSMO | |
| Trifluoroacetic Acid SCHEMBL1874603 | 0.89 | SLC2A1 (0.42) | SLC2A1SMOHTR5A | |
| Trifluoroacetic Acid SCHEMBL1874447 | 0.87 | SMO (0.41) | SLC2A1MTNR1AMTNR1BSMOCA1 | |
| Trifluoroacetic Acid SCHEMBL1877883 | 0.87 | SLC2A1 (0.44) | DRD2SLC2A1HTR5A | |
| Trifluoroacetic Acid SCHEMBL1875501 | 0.85 | CACNA1B (0.37) | SLC2A1SMOHTR5A | |
| SCHEMBL12634056 | 0.85 | DRD2 (0.48) | DRD2 | |
| Trifluoroacetic Acid SCHEMBL1875942 | 0.85 | OPRM1 (0.39) | SLC2A1SMOHTR5A | |
| Trifluoroacetic Acid SCHEMBL1879953 | 0.85 | OPRM1 (0.39) | SLC2A1SMOHTR5A | |
| Trifluoroacetic Acid SCHEMBL1872774 | 0.83 | SLC2A1 (0.40) | SLC2A1SMOHTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |