Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 3/20 | 0.31 |
| ▸ | FAP | Q12884 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23394429 | 0.85 | PIK3CA (0.32) | DPP4 | |
| SCHEMBL23394685 | 0.79 | PREP (0.37) | DPP4PREPFAP | |
| SCHEMBL18771926 | 0.78 | PREP (0.32) | PREPFAP | |
| SCHEMBL18675246 | 0.76 | PIK3CA (0.37) | DPP4PREPFAPALDH1A1 | |
| SCHEMBL883412 | 0.70 | ELANE (0.39) | — | |
| SCHEMBL8133669 | 0.68 | PREP (0.41) | PREPFAP | |
| SCHEMBL17282592 | 0.65 | PREP (0.49) | DPP4PREPFAP | |
| SCHEMBL12943482 | 0.65 | PIK3CA (0.39) | — | |
| SCHEMBL20629567 | 0.65 | PIK3CA (0.39) | DPP4 | |
| SCHEMBL18681115 | 0.64 | PREP (0.36) | DPP4PREPFAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159345-A1 | INHIBITORS OF HEPATITIS C VIRUS | Gilead Sciences, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |