Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.37 |
| ▸ | FAP | Q12884 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 7/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 7/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 6/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 6/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.33 |
| ▸ | GRB2 | P62993 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18675246 | 0.86 | PIK3CA (0.37) | PREPFAPPIK3CAPIK3CBTACR1 | |
| SCHEMBL21086436 | 0.82 | PREP (0.35) | PREPFAPTACR1ITGB3ITGA2B | |
| SCHEMBL20629567 | 0.82 | PIK3CA (0.39) | PIK3CAPIK3CBTACR1PIK3CDPIK3CG | |
| SCHEMBL23394561 | 0.80 | CCKBR (0.34) | PREPFAPTACR1ITGB3ITGA2B | |
| SCHEMBL18771926 | 0.79 | PREP (0.32) | PREPFAPPIK3CAPIK3CBPIK3CD | |
| SCHEMBL18771568 | 0.79 | DPP4 (0.31) | PREPFAPDPP4 | |
| SCHEMBL26616440 | 0.75 | PREP (0.47) | PREPFAP | |
| SCHEMBL26616445 | 0.75 | PREP (0.47) | PREPFAP | |
| SCHEMBL26616435 | 0.75 | PREP (0.47) | PREPFAP | |
| SCHEMBL17282592 | 0.73 | PREP (0.49) | PREPFAPPIK3CAPIK3CBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3825312-A1 | INTERMEDIATES FOR PREPARING INHIBITORS OF HEPATITIS C VIRUS | Gilead Pharmasset LLC (US) | 2021-05-26 | — | — | EP | disclosed |