Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 18/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18772107 | 0.92 | TLR8 (0.50) | TLR8TLR7 | |
| SCHEMBL18771796 | 0.87 | TLR8 (0.58) | TLR8TLR7 | |
| SCHEMBL18772121 | 0.87 | TLR8 (0.52) | TLR8TLR7ALDH1A1HPGD | |
| SCHEMBL12619300 | 0.87 | TLR8 (0.64) | TLR8TLR7 | |
| SCHEMBL18771832 | 0.84 | TLR8 (0.54) | TLR8TLR7 | |
| SCHEMBL18772025 | 0.82 | TLR8 (0.51) | TLR8TLR7 | |
| SCHEMBL18771830 | 0.81 | TLR8 (0.57) | TLR8TLR7 | |
| SCHEMBL18772200 | 0.81 | TLR8 (0.50) | TLR8TLR7ALDH1A1 | |
| SCHEMBL18772071 | 0.81 | TLR8 (0.46) | TLR8TLR7ALDH1A1MAPT | |
| SCHEMBL18771925 | 0.80 | TLR8 (0.45) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159337-A2 | SUBSTITUTED BENZOAZEPINES AS TOLL-LIKE RECEPTOR MODULATORS | Ventirx Pharmaceuticals, Inc. (US) | 2017-04-26 | — | — | EP | disclosed |