SCHEMBL18772409 — predicted protein targets

Predicted protein targets (top 13)

	gene	UniProt	supporting neighbours	confidence
▸	ACHE	P22303	12/20	0.58

▸	HSP90AB1	P08238	4/20	0.39

▸	SOD1	P00441	1/20	0.38

▸	HSP90AA1	P07900	3/20	0.38

▸	LMNA	P02545	2/20	0.36

▸	TRPA1	O75762	1/20	0.34

▸	CHRM1	P11229	1/20	0.34

▸	SLC6A2	P23975	1/20	0.34

▸	ADRA1A	P35348	1/20	0.34

▸	HTR2B	P41595	1/20	0.34

▸	CYP1A2	P05177	1/20	0.34

▸	CYP3A4	P08684	1/20	0.34

▸	CYP2B6	P20813	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL15931778	0.83	ACHE (0.51)	ACHEHSP90AB1LMNA
SCHEMBL8091521	0.82	ACHE (0.69)	ACHE
SCHEMBL8099829	0.82	ACHE (0.69)	ACHE
SCHEMBL14645796	0.73	ACHE (0.50)	ACHEHSP90AB1
SCHEMBL7041619	0.72	ACHE (0.61)	ACHE
SCHEMBL15822170	0.71	ACHE (0.62)	ACHELMNATRPA1CYP3A4
SCHEMBL6058839	0.71	ACHE (0.53)	ACHELMNACYP3A4
SCHEMBL29621066	0.71	ACHE (0.61)	ACHE
SCHEMBL20692255	0.71	ACHE (0.59)	ACHE
SCHEMBL3658017	0.71	ACHE (0.61)	ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9630980-B2	Asymmetrical ligands	BOREALIS AG (AT)	2017-04-25	—	—	US	disclosed