Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | ATM | Q13315 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | APEX1 | P27695 | 1/20 | 0.64 |
| ▸ | TAAR1 | Q96RJ0 | 5/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31090146 | 0.90 | GAA (0.77) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL13181092 | 0.85 | GAA (0.69) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL2019108 | 0.85 | KDM4E (0.72) | KDM4EATMTSHRCYP3A4CYP1A2 | |
| SCHEMBL29351641 | 0.84 | ATM (1.00) | KDM4EATMTSHRCYP3A4CYP1A2 | |
| SCHEMBL1725006 | 0.84 | GAA (0.74) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL210639 | 0.84 | ATM (1.00) | KDM4EATMTSHRCYP3A4CYP1A2 | |
| SCHEMBL687841 | 0.83 | GAA (0.67) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL8867396 | 0.83 | GAA (0.67) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL30135970 | 0.83 | GAA (0.67) | KDM4EATMGAATSHRCYP3A4 | |
| SCHEMBL28186288 | 0.83 | GAA (0.67) | KDM4EATMGAATSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-26 | — | — | US | disclosed |
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2018-04-26 | — | — | US | disclosed |
| WO-2016167511-A2 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2016-10-20 | — | — | WO | disclosed |
| US-20110207860-A1 | Inkjet Ink Compositions Comprising Polymeric Dispersants Having Attached Chromophore Groups | CABOT CORPORATION (US) | 2011-08-25 | — | — | US | disclosed |
| US-20110207860-A1 | Inkjet Ink Compositions Comprising Polymeric Dispersants Having Attached Chromophore Groups | CABOT CORPORATION (US) | 2011-08-25 | — | — | US | disclosed |
| US-7947761-B2 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947761-B2 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION (US) | 2011-05-24 | — | — | US | disclosed |
| US-7947761-B2 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION (US) | 2011-05-24 | — | — | US | disclosed |
| EP-1981943-A1 | INKJET INK COMPOSITIONS COMPRISING POLYMERIC DISPERSANTS HAVING ATTACHED CHROMOPHORE GROUPS | Cabot Corporation (US) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007089859-A1 | INKJET INK COMPOSITIONS COMPRISING POLYMERIC DISPERSANTS HAVING ATTACHED CHROMOPHORE GROUPS | CABOT CORPORATION (US) | 2007-08-09 | — | — | WO | disclosed |
| US-20070179214-A1 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION | 2007-08-02 | — | — | US | disclosed |
| US-20070179215-A1 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION | 2007-08-02 | — | — | US | disclosed |
| US-20070179215-A1 | Inkjet ink compositions comprising polymeric dispersants having attached chromophore groups | CABOT CORPORATION | 2007-08-02 | — | — | US | disclosed |
| CN-1075808-C | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2001-12-05 | — | — | CN | disclosed |
| CN-1310169-A | Anils with nitric oxide synzyme inhibiting function | SHUGAI SEIYAKU K K (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1172473-A | Aniline derivatives having nitric oxide synthase inhibitory activity | CHUGAI PHARMACEUTICAL CO LTD (JP) | 1998-02-04 | — | — | CN | disclosed |
| EP-0175525-B1 | 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BEECHAM CORPORATION (US) | 1990-05-23 | — | — | EP | disclosed |
| US-4593106-A | 4-[2-(dialkylamino)ethyl]-7-hydroxyisatins | SMITHKLINE BECKMAN CORPORATION (US) | 1986-06-03 | — | — | US | disclosed |
| EP-0175525-A1 | 7-[2-(Dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BEECHAM CORPORATION (US) | 1986-03-26 | — | — | EP | disclosed |
| US-4554287-A | Antihypertensive 7-[2-(dialkylamino)ethyl]-4-hydroxy-1,3-benzimidazol-2-ones | SMITHKLINE BECKMAN CORPORATION (US) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180111905-A1 | N2-(2-METHOXYPHENYL)PYRIMIDINE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION FOR CANCER PREVENTION OR TREATMENT CONTAINING SAME AS ACTIVE INGREDIENT | ALK, NPM1, EML4 | KDM4E 756/4885ATM 1285/4885GAA 3276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.