Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | APEX1 | P27695 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL687450 | 0.92 | GAA (0.57) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL358592 | 0.89 | GAA (0.62) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL31090146 | 0.88 | GAA (0.77) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL8868058 | 0.85 | ALDH1A1 (0.67) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL2888639 | 0.85 | GAA (0.71) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL13181092 | 0.83 | GAA (0.69) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL1877259 | 0.83 | KDM4E (0.72) | GAACYP19A1ALDH1A1CYP3A4TSHR | |
| SCHEMBL296593 | 0.82 | ATM (0.66) | CYP19A1ALDH1A1CYP3A4CYP1A2KDM4E | |
| SCHEMBL13098004 | 0.82 | ATM (0.66) | CYP19A1ALDH1A1CYP3A4CYP1A2KDM4E | |
| SCHEMBL29446268 | 0.82 | ATM (0.66) | CYP19A1ALDH1A1CYP3A4CYP1A2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1637122-B1 | 2-(Amino or substituted Amino)-3-5-6-substituted Phenol compounds, dyeing compositions containing them, and use thereof | PROCTER & GAMBLE (US) | 2012-02-29 | — | — | EP | claimed |
| EP-1634572-B1 | Hair dyeing compositions comprising 2-Amino-3-5-substituted phenol compounds and use thereof | PROCTER & GAMBLE (US) | 2010-04-07 | — | — | EP | claimed |
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | HENKEL AG & CO. KGAA (DE) | 2018-06-26 | — | — | US | disclosed |
| US-9809668-B2 | Polymerizable compound, composition, polymer, optically anisotropic body, liquid crystal display device, and organic EL device | DIC CORPORATION (JP) | 2017-11-07 | — | — | US | disclosed |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | HENKEL AG & CO. KGAA (DE) | 2017-08-17 | — | — | US | disclosed |
| US-20170029655-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | DIC CORPORATION (JP) | 2017-02-02 | — | — | US | disclosed |
| US-20170002123-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | DIC CORPORATION (JP) | 2017-01-05 | — | — | US | disclosed |
| EP-0924194-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-05-14 | — | — | EP | disclosed |
| EP-0924193-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0939134-B1 | Processes for producing optically active 2-amino-1-phenylethanol derivatives | DAICEL CHEM (JP) | 2002-09-11 | — | — | EP | disclosed |
| US-5686484-A | ANTHELMINTICS, ACARICIDES, INSECTICIDES | SANKYO CO., LTD. (JP) | 1997-11-11 | — | — | US | disclosed |
| US-4854935-A | OXIDATION COLOR DYE COUPLERS | WELLA AKTIENGESELLSCHAFT (DE) | 1989-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10004672-B2 | Oxidation dye including a combination of cross-linked, aminated siloxane polymers and non-ionic surfactants | KRT18, PLOD3, SORD | GAA 3867/4885CYP19A1 1236/4885ALDH1A1 106/4885 |
| US-20170231880-A1 | OXIDATION DYE INCLUDING A COMBINATION OF CROSS-LINKED, AMINATED SILOXANE POLYMERS AND NON-IONIC SURFACTANTS | KRT18, PLOD3, SORD | GAA 3867/4885CYP19A1 1236/4885ALDH1A1 106/4885 |
| US-20170002123-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | OCIAD1, OCIAD2, ELOC | GAA 3310/4885CYP19A1 2599/4885ALDH1A1 3129/4885 |
| US-20170029655-A1 | POLYMERIZABLE COMPOUND, COMPOSITION, POLYMER, OPTICALLY ANISOTROPIC BODY, LIQUID CRYSTAL DISPLAY DEVICE, AND ORGANIC EL DEVICE | OCIAD1, OCIAD2, ELOC | GAA 3310/4885CYP19A1 2599/4885ALDH1A1 3129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.