Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.42 |
| ▸ | NMT2 | O60551 | 1/20 | 0.40 |
| ▸ | NMT1 | P30419 | 1/20 | 0.40 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.39 |
| ▸ | NPY4R | P50391 | 4/20 | 0.39 |
| ▸ | NPY1R | P25929 | 3/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.39 |
| ▸ | NPY2R | P49146 | 2/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 3/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19085021 | 0.96 | TFPI (0.41) | TFPITLR2NMT2NMT1QRFPR | |
| SCHEMBL18773409 | 0.90 | TFPI (0.43) | TFPITLR2NPY4RNPY1RNPY5R | |
| SCHEMBL19084487 | 0.90 | TFPI (0.44) | TFPITLR2NPY4RNPY1RNPY5R | |
| SCHEMBL19084491 | 0.86 | TFPI (0.41) | TFPINPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL19084899 | 0.85 | TFPI (0.42) | TFPINPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL19084913 | 0.84 | OPRL1 (0.40) | TFPIIL23ROPRL1RXFP1 | |
| SCHEMBL10168798 | 0.84 | TFPI (0.51) | TFPINPY4RNPY1RNPY5RNPY2R | |
| SCHEMBL10168602 | 0.83 | TFPI (0.53) | TFPINMT2NMT1NPY4RNPY1R | |
| SCHEMBL19791184 | 0.82 | QRFPR (0.38) | TFPITLR2NMT2NMT1QRFPR | |
| SCHEMBL19791180 | 0.82 | QRFPR (0.38) | TFPITLR2NMT2NMT1QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951103-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2018-04-24 | — | — | US | disclosed |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2017-07-06 | — | — | US | disclosed |
| US-9630991-B2 | βsheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2017-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | TFPI 3734/4885TLR2 4880/4885NMT2 1239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.