Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TFPI | P10646 | 1/20 | 0.41 |
| ▸ | NPY4R | P50391 | 6/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 6/20 | 0.41 |
| ▸ | NPY1R | P25929 | 5/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.40 |
| ▸ | BMP1 | P13497 | 1/20 | 0.39 |
| ▸ | IL23R | Q5VWK5 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773409 | 0.96 | TFPI (0.43) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL19084899 | 0.91 | TFPI (0.42) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL19085021 | 0.90 | TFPI (0.41) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL19084487 | 0.87 | TFPI (0.44) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL18773238 | 0.86 | TFPI (0.43) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL10168798 | 0.85 | TFPI (0.51) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL12070950 | 0.84 | SIRT5 (0.53) | TFPINPY4RNPY5RNPY1RNPY2R | |
| SCHEMBL30773902 | 0.83 | NPY4R (0.48) | NPY4RNPY5RNPY1RNPY2RNOD1 | |
| SCHEMBL30773898 | 0.83 | NPY4R (0.48) | NPY4RNPY5RNPY1RNPY2RNOD1 | |
| SCHEMBL20806247 | 0.83 | NPY4R (0.45) | TFPINPY4RNPY5RNPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951103-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2018-04-24 | — | — | US | disclosed |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | TFPI 3734/4885NPY4R 3046/4885NPY5R 3339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.