Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 5/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.40 |
| ▸ | TFPI | P10646 | 1/20 | 0.40 |
| ▸ | IL23R | Q5VWK5 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18773431 | 0.93 | TFPI (0.42) | OPRL1KEAP1TFPIIL23RRXFP1 | |
| SCHEMBL18773423 | 0.89 | KEAP1 (0.41) | OPRL1KEAP1TFPIIL23RRXFP1 | |
| SCHEMBL18773409 | 0.84 | TFPI (0.43) | KEAP1TFPIIL23RRXFP1 | |
| SCHEMBL18773238 | 0.84 | TFPI (0.43) | OPRL1TFPIIL23RRXFP1 | |
| SCHEMBL19084487 | 0.83 | TFPI (0.44) | OPRL1KEAP1TFPIIL23RRXFP1 | |
| SCHEMBL19084491 | 0.80 | TFPI (0.41) | KEAP1TFPIIL23RRXFP1 | |
| SCHEMBL19085021 | 0.80 | TFPI (0.41) | KEAP1TFPIIL23R | |
| SCHEMBL10168798 | 0.80 | TFPI (0.51) | TFPIRXFP1 | |
| SCHEMBL19084899 | 0.79 | TFPI (0.42) | KEAP1TFPI | |
| SCHEMBL30942619 | 0.79 | IL23R (0.48) | TFPIIL23RRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9951103-B2 | Beta sheet tapes ribbons in tissue engineering | UNIVERSITY OF LEEDS (GB) | 2018-04-24 | — | — | US | disclosed |
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | UNIVERSITY OF LEEDS (GB) | 2017-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190740-A1 | BETA SHEET TAPES RIBBONS IN TISSUE ENGINEERING | IAPP, KRT18, TAGLN2 | OPRL1 3870/4885KEAP1 3959/4885TFPI 3734/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.