Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RGS12 | O14924 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21005614 | 0.77 | KDM4E (0.39) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL13694979 | 0.75 | KDM4A (0.47) | SMN1; SMN2RAB9AAPPPOLBALDH1A1 | |
| SCHEMBL14401399 | 0.72 | TUBB1 (0.42) | RAB9APOLBNPC1 | |
| SCHEMBL15581674 | 0.71 | CHRM2 (0.40) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL15624278 | 0.71 | CTSZ (0.41) | RAB9APOLBALDH1A1NPC1MAPT | |
| SCHEMBL16538525 | 0.71 | KMT2A (0.43) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL16538523 | 0.71 | KMT2A (0.43) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL19649133 | 0.67 | POLB (0.36) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL13695034 | 0.67 | ALDH1A1 (0.42) | SMN1; SMN2RAB9APOLBALDH1A1NPC1 | |
| SCHEMBL15581675 | 0.66 | CTSZ (0.39) | RAB9APOLBALDH1A1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2677995-B1 | COMPOSITION FOR DYEING KERATIN FIBRES COMPRISING A DIRECT DYE BEARING A DISULFIDE/THIOL FUNCTION, A NONIONIC SURFACTANT, AN AMPHOTERIC SURFACTANT, AN ALKALINE AGENT AND A REDUCING AGENT | L'ORÉAL (FR) | 2017-04-26 | — | — | EP | disclosed |