Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MET | P08581 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17199516 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL18774628 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL18761863 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL17199453 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL18761949 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL18781533 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL18781521 | 1.00 | POLB (0.32) | POLBL3MBTL1METACHE | |
| SCHEMBL25204744 | 0.90 | POLB (0.33) | POLBMET | |
| SCHEMBL18387559 | 0.78 | ALDH1A1 (0.39) | — | |
| SCHEMBL16974776 | 0.78 | ACHE (0.42) | L3MBTL1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114077-A1 | HETEROCYCLIC KINASE INHIBITORS | ABBVIE INC. | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114077-A1 | HETEROCYCLIC KINASE INHIBITORS | MAP3K1, MAP3K20, MAP3K19 | POLB 2622/4885L3MBTL1 3552/4885MET 624/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.