Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fosphenytoin SCHEMBL20769774 | 0.89 | POLB (0.56) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL94254 | 0.89 | POLB (0.56) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL1560790 | 0.88 | POLB (0.55) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL318673 | 0.88 | POLB (0.55) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL7205444 | 0.88 | POLB (0.55) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL28132875 | 0.82 | POLB (0.49) | POLBTDP1NPC1MEN1KMT2A | |
| SCHEMBL2615240 | 0.82 | POLB (0.49) | POLBTDP1NPC1MEN1KMT2A | |
| Fosphenytoin SCHEMBL5798533 | 0.81 | CYP2C9 (0.52) | POLBTDP1NPC1MEN1KMT2A | |
| SCHEMBL1725500 | 0.81 | POLB (0.55) | POLBTDP1NPC1MEN1KMT2A | |
| SCHEMBL17131153 | 0.81 | POLB (0.58) | POLBTDP1NPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
| US-20170112948-A1 | Inorganic-organic hybrid compound | Karlsruher Institut für Technologie (DE) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112948-A1 | Inorganic-organic hybrid compound | SLCO4C1, SLCO2A1, SLCO1A2 | POLB 3337/4885TDP1 3934/4885NPC1 277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.