Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.64 |
| ▸ | PER2 | O15055 | 1/20 | 0.45 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5251280 | 0.92 | HTR2A (0.67) | HTR2AHTR1ATMEM97PER2CRY2 | |
| SCHEMBL5251275 | 0.92 | HTR2A (0.67) | HTR2AHTR1ATMEM97PER2CRY2 | |
| Hydrochloric Acid SCHEMBL5248235 | 0.91 | HTR2A (0.66) | HTR2AHTR1ATMEM97PER2CRY2 | |
| Hydrochloric Acid SCHEMBL5248229 | 0.91 | HTR2A (0.66) | HTR2AHTR1ATMEM97PER2CRY2 | |
| SCHEMBL17335753 | 0.83 | HTR1A (0.57) | HTR2AHTR1ATMEM97ACHESCN1A | |
| SCHEMBL5255967 | 0.82 | HTR1A (0.53) | HTR2AHTR1ATMEM97PER2CRY2 | |
| SCHEMBL5255966 | 0.82 | HTR1A (0.53) | HTR2AHTR1ATMEM97PER2CRY2 | |
| Hydrochloric Acid SCHEMBL5253393 | 0.81 | HTR1A (0.52) | HTR2AHTR1ATMEM97PER2CRY2 | |
| Hydrochloric Acid SCHEMBL5253389 | 0.81 | HTR1A (0.52) | HTR2AHTR1ATMEM97PER2CRY2 | |
| SCHEMBL5656314 | 0.80 | HTR2A (0.70) | HTR2AHTR1ATMEM97ACHEPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114037-A1 | COMPOUNDS AND METHODS OF USE TO TREAT SCHIZOPHRENIA | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114037-A1 | COMPOUNDS AND METHODS OF USE TO TREAT SCHIZOPHRENIA | SIGMAR1, GRIN2C, OPRL1 | HTR2A 78/4885HTR1A 66/4885TMEM97 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.