Phenyldifluoromethanesulfonamide

Phenyldifluoromethanesulfonamide

SCHEMBL187768

NS(=O)(=O)C(F)(F)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CA1 P00915 14/20 1.00
CA2 P00918 14/20 1.00
CA9 Q16790 11/20 1.00
CA5A P35218 9/20 1.00
ALDH1A1 P00352 1/20 0.46
TSHR P16473 1/20 0.46
PTPN1 P18031 3/20 0.43
CA7 P43166 3/20 0.42
CA12 O43570 3/20 0.42
CA13 Q8N1Q1 2/20 0.42
CA14 Q9ULX7 2/20 0.42
CA3 P07451 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
PLA2G7 Q13093 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
KCNN4 O15554 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4124865 0.80 CA1 (0.67) CA1CA2CA9CA5AALDH1A1
SCHEMBL18316472 0.78 CA1 (0.64) CA1CA2CA9CA5AALDH1A1
Trifluoromethylbenzene SCHEMBL27721404 0.78 TSHR (0.70) CA1CA2CA9CA5AALDH1A1
SCHEMBL7126033 0.76 CA1 (0.61) CA1CA2CA9CA5AALDH1A1
SCHEMBL3870301 0.76 PTPN1 (0.67) CA1CA2CA9CA5AALDH1A1
SCHEMBL6241031 0.75 CA2 (0.60) CA1CA2CA9CA5AALDH1A1
SCHEMBL27704938 0.75 CA2 (0.60) CA1CA2CA9CA5AALDH1A1
SCHEMBL6467896 0.73 CA2 (0.58) CA1CA2CA9CA5AALDH1A1
SCHEMBL296761 0.73 CA2 (0.57) CA1CA2CA9CA5AALDH1A1
SCHEMBL2990556 0.73 CA1 (0.57) CA1CA2CA9CA5AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110035660-B Herbicidal combination containing triafamone and indoxachlor 拜耳作物科学股份公司 2021-10-26 CN disclosed
WO-2020119590-A1 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. 中国科学院上海药物研究所 2020-06-18 WO disclosed
WO-2020119590-A1 3-CYANOPYRIDINE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USES THEREOF. 中国科学院上海药物研究所 2020-06-18 WO disclosed
WO-2018104142-A1 HERBICIDAL COMBINATION CONTAINING TRIAFAMONE AND INDAZIFLAM BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2018-06-14 WO disclosed
WO-2012052408-A2 HERBICIDE COMBINATION WITH A DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULPHONYLANILIDE BAYER CROPSCIENCE AG (DE) 2012-04-26 WO disclosed
US-8158559-B2 Herbicidal combination comprising dimethoxytriazinyl-substituted difluoromethanesulfonylanilides BAYER CROPSCIENCE AG (DE) 2012-04-17 US disclosed
EP-2317855-B1 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2012-01-04 EP disclosed
US-20110177946-A1 HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-07-21 US disclosed
US-20110172100-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2011-07-14 US disclosed
EP-2328415-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES Bayer CropScience AG (DE) 2011-06-08 EP disclosed
WO-2010017923-A2 HERBICIDAL COMBINATION WITH DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017928-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017929-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017925-A2 HERBICIDAL-SAFENER-COMBINATION COMPRISING DIMETHOXYTRIAZINYL- SUBSTITUTED DIFLUORMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017927-A2 HERBICIDAL COMBINATION COMRPISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017926-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017930-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017924-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017921-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed
WO-2010017922-A2 HERBICIDAL COMBINATION COMPRISING DIMETHOXY-TRIAZINYL-SUBSTITUTED DIFLUOROMETHANE SULFONYLANILIDES BAYER CROPSCIENCE AG (DE) 2010-02-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110172100-A1 HERBICIDAL COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES DPYD, ATL3, DDT CA1 2092/4885CA2 684/4885CA9 2521/4885
US-20110177946-A1 HERBICIDE COMBINATION COMPRISING DIMETHOXYTRIAZINYL-SUBSTITUTED DIFLUOROMETHANESULFONYLANILIDES DPYD, ATL3, IDH1 CA1 2062/4885CA2 796/4885CA9 2375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.