SCHEMBL2990556

SCHEMBL2990556

O=S(=O)(OF)C(F)(F)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 5/20 0.57
CA2 P00918 5/20 0.57
CA5A P35218 5/20 0.57
CA9 Q16790 5/20 0.57
TSHR P16473 2/20 0.42
ALDH1A1 P00352 1/20 0.42
PTPN1 P18031 3/20 0.41
HSD11B1 P28845 1/20 0.33
MAPK1 P28482 1/20 0.33
RIPK1 Q13546 1/20 0.33
NR3C1 P04150 1/20 0.33
PGR P06401 1/20 0.33
AR P10275 1/20 0.33
ESR2 Q92731 1/20 0.33
KCNN4 O15554 2/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
KIF11 P52732 1/20 0.32
HTR6 P50406 1/20 0.32
NR1H2 P55055 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4124865 0.77 CA1 (0.67) CA1CA2CA5ACA9TSHR
SCHEMBL18316472 0.75 CA1 (0.64) CA1CA2CA5ACA9TSHR
SCHEMBL3128891 0.74 SLC22A12 (0.39) CA1CA2CA5ACA9HSD11B1
SCHEMBL3870301 0.73 PTPN1 (0.67) CA1CA2CA5ACA9TSHR
SCHEMBL7126033 0.73 CA1 (0.61) CA1CA2CA5ACA9TSHR
Phenyldifluoromethanesulfonamide SCHEMBL187768 0.73 CA1 (1.00) CA1CA2CA5ACA9TSHR
SCHEMBL759936 0.71 HTR6 (0.39) CA1CA2CA5ACA9TSHR
SCHEMBL2340409 0.70 CA1 (0.47) CA1CA2CA5ACA9TSHR
SCHEMBL296761 0.70 CA2 (0.57) CA1CA2CA5ACA9TSHR
SCHEMBL3132299 0.70 CA2 (0.47) CA1CA2CA5ACA9TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116803505-B Dehydrogenation catalyst, preparation method and application thereof in preparation of carbazole through diphenylamine dehydrogenation 北京海望氢能科技有限公司 2024-03-26 CN disclosed
CN-116803505-A Dehydrogenation catalyst, preparation method and application thereof in preparation of carbazole through diphenylamine dehydrogenation 北京海望氢能科技有限公司 2023-09-26 CN disclosed
US-20140011097-A1 TERT-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME UBE INDUSTRIES, LTD. (JP) 2014-01-09 US disclosed
US-8546599-B2 Tert-butylphenyl sulfonate compound, nonaqueous electrolyte solution for lithium secondary battery using the same, and lithium secondary battery using the same UBE INDUSTRIES, LTD. (JP) 2013-10-01 US disclosed
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME MU IONIC SOLUTIONS CORPORATION (JP) 2010-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100055576-A1 tert-BUTYLPHENYL SULFONATE COMPOUND, NONAQUEOUS ELECTROLYTE SOLUTION FOR LITHIUM SECONDARY BATTERY USING THE SAME, AND LITHIUM SECONDARY BATTERY USING THE SAME TERT, TST, TES CA1 3264/4885CA2 2362/4885CA5A 3634/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.