SCHEMBL18778135

SCHEMBL18778135

c1ccc(-n2c3ccccc3c3ccc(-c4cccc(-c5cccc(-c6cccc(-c7cnc8c9ccccc9c9ccccc9c8n7)c6)c5)c4)cc32)cc1

nearest known ligand 0.42

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 1/20 0.42
ATM Q13315 1/20 0.42
ASIC3 Q9UHC3 1/20 0.34
ALDH1A1 P00352 2/20 0.33
MAP3K11 Q16584 1/20 0.33
TSHR P16473 1/20 0.33
CYP2C19 P33261 1/20 0.33
KMT2A Q03164 3/20 0.32
IL1R1 P14778 1/20 0.32
MEN1 O00255 2/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HTT P42858 1/20 0.32
ATR Q13535 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31
KHK P50053 1/20 0.31
LIMK1 P53667 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268694 1.00 L3MBTL1 (0.42) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778454 1.00 L3MBTL1 (0.42) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778269 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778385 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778262 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778388 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778323 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778329 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778452 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1
SCHEMBL18778257 0.99 KDM4E (0.41) L3MBTL1KDM4EATMASIC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-12-06 US disclosed
WO-2017068457-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 WO disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device RECQL, HSF1, DDX41 L3MBTL1 1123/4885KDM4E 2319/4885ATM 1948/4885
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device RECQL, HSF1, DDX41 L3MBTL1 1123/4885KDM4E 2319/4885ATM 1948/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.