SCHEMBL18778385

SCHEMBL18778385

c1ccc(-n2c3ccccc3c3ccc(-c4ccc(-c5cccc(-c6ccc(-c7cccc(-c8cnc9c%10ccccc%10c%10ccccc%10c9n8)c7)cc6)c5)cc4)cc32)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ASIC3 Q9UHC3 1/20 0.35
LIMK1 P53667 1/20 0.33
MAP3K11 Q16584 1/20 0.32
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
HSP90AA1 P07900 1/20 0.32
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TSHR P16473 1/20 0.32
CYP2C19 P33261 1/20 0.32
AVPR1A P37288 1/20 0.32
HDAC4 P56524 1/20 0.32
IL1R1 P14778 1/20 0.32
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18778351 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778260 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778257 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778388 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778329 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778323 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778262 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778269 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778452 1.00 KDM4E (0.41) KDM4EATML3MBTL1ASIC3LIMK1
SCHEMBL18778135 0.99 L3MBTL1 (0.42) KDM4EATML3MBTL1ASIC3LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2022-12-06 US disclosed
WO-2017068457-A1 HETEROCYCLIC COMPOUND, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE, ELECTRONIC DEVICE, AND LIGHTING DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 WO disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 US disclosed
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-04-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170117487-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device RECQL, HSF1, DDX41 KDM4E 2319/4885ATM 1948/4885L3MBTL1 1123/4885
US-11522138-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device RECQL, HSF1, DDX41 KDM4E 2319/4885ATM 1948/4885L3MBTL1 1123/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.