SCHEMBL1877874

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL21681878	0.92	ESR1 (0.65)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL21681866	0.91	ESR1 (0.73)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL10782190	0.91	ESR1 (0.78)	ESR1ESR2NSD2MAPTKMT2A
	Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL78117	0.89	ESR1 (0.71)	ESR1ESR2NSD2MAPTKMT2A
	Benzoic Acid 3-Hydroxyphenyl Ester SCHEMBL31650796	0.89	ESR1 (0.71)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL9010694	0.89	ESR1 (0.61)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL69684	0.88	NSD2 (0.63)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL21114373	0.88	ESR1 (0.69)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL8205804	0.88	CA12 (0.61)	ESR1ESR2NSD2MAPTKMT2A
	SCHEMBL11871223	0.87	MAPT (0.59)	ESR1ESR2NSD2MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.