Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | SLC2A4 | P14672 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.51 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21681878 | 0.96 | ESR1 (0.65) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL687865 | 0.92 | KMT2A (0.56) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL1877874 | 0.89 | ESR1 (0.66) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL8205804 | 0.88 | CA12 (0.61) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL10921643 | 0.88 | KMT2A (0.61) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL11871223 | 0.87 | MAPT (0.59) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL10456285 | 0.87 | MAPT (0.59) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL10782190 | 0.87 | ESR1 (0.78) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL21681866 | 0.87 | ESR1 (0.73) | ESR1ESR2KMT2AMEN1CASP3 | |
| SCHEMBL9435811 | 0.86 | CA12 (0.53) | ESR1ESR2KMT2AMEN1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890897-A | PDE2 inhibitor lactone derivative and preparation method thereof | 常州大学 | 2022-08-12 | — | — | CN | disclosed |
| US-5519106-A | COLORLESS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5455324-A | Containing reduced amounts of benzophenone and benzoate ester derivatives | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-03 | — | — | US | disclosed |
| EP-0584801-A2 | Aromatic polycarbonate resins and process for the preparation thereof | Mitsubishi Chemical Corporation (JP) | 1994-03-02 | — | — | EP | disclosed |
| EP-0052927-B1 | STRETCHED FILM STRUCTURE OF THE POLY-1,3-PHENYLENE TEREPHTHALATE TYPE | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1987-01-07 | — | — | EP | disclosed |
| US-4390683-A | Stretched film structure of the poly-1,3-phenylene terephthalate type | MITSUI PETROCHEMICAL INDUSTRIES LTD. (JP) | 1983-06-28 | — | — | US | disclosed |
| EP-0052927-A2 | Stretched film structure of the poly-1,3-phenylene terephthalate type | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1982-06-02 | — | — | EP | disclosed |