SCHEMBL18779641

SCHEMBL18779641

c1ccc(-c2ccc3c4ccc(-c5ccc6c7ccccc7n(-c7ccccc7)c6c5)cc4n(-c4ccccc4)c3c2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.67
KDM4E B2RXH2 1/20 0.67
ATM Q13315 1/20 0.67
KMT2A Q03164 3/20 0.45
IL1R1 P14778 1/20 0.45
MEN1 O00255 2/20 0.44
MAPT P10636 2/20 0.44
ALDH1A1 P00352 1/20 0.44
HTT P42858 1/20 0.44
HDAC4 P56524 1/20 0.43
AVPR1A P37288 1/20 0.43
RXRA P19793 1/20 0.43
RXRB P28702 1/20 0.43
MAOB P27338 1/20 0.39
HSP90AA1 P07900 1/20 0.39
MAPK1 P28482 1/20 0.38
MAPK8 P45983 2/20 0.38
TSPO P30536 1/20 0.38
PGR P06401 1/20 0.38
MAPK9 P45984 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18042083 1.00 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16491834 1.00 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL21578499 0.98 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15850636 0.98 L3MBTL1 (0.64) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17228128 0.98 L3MBTL1 (0.69) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL25655288 0.96 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18962948 0.96 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18020740 0.96 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18505028 0.96 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL16901212 0.96 L3MBTL1 (0.61) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed
US-20170117488-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-04-27 US disclosed