SCHEMBL18505028

SCHEMBL18505028

c1ccc(-c2ccc3c4cc5c(cc4n(-c4ccccc4)c3c2)c2ccccc2n5-c2ccccc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
KDM4E B2RXH2 1/20 0.62
ATM Q13315 1/20 0.62
KMT2A Q03164 3/20 0.43
IL1R1 P14778 1/20 0.43
MEN1 O00255 2/20 0.42
MAPT P10636 2/20 0.42
ALDH1A1 P00352 1/20 0.42
HTT P42858 1/20 0.42
HDAC4 P56524 1/20 0.42
RXRA P19793 1/20 0.41
RXRB P28702 1/20 0.41
AVPR1A P37288 1/20 0.41
TSPO P30536 1/20 0.39
MAOB P27338 1/20 0.37
HSP90AA1 P07900 1/20 0.37
MAPK8 P45983 2/20 0.36
MAPK1 P28482 1/20 0.36
DNM1 Q05193 1/20 0.36
PGR P06401 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19863531 0.98 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL27424098 0.98 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23008249 0.98 L3MBTL1 (0.60) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19769555 0.97 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL15763779 0.97 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL23008263 0.97 L3MBTL1 (0.57) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19797680 0.97 L3MBTL1 (0.62) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18042083 0.96 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL19501101 0.96 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL18779641 0.96 L3MBTL1 (0.67) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230020540-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2023-01-19 US disclosed
US-10749119-B2 Plurality of host materials and organic electroluminescent device comprising the same ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD (KR) 2020-08-18 US disclosed
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-02-01 US disclosed
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2018-02-01 US disclosed
US-20170047527-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-02-16 US disclosed
US-20170047527-A1 MULTI-COMPONENT HOST MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2017-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10749119-B2 Plurality of host materials and organic electroluminescent device comprising the same SOD1, L3MBTL4, TELO2 L3MBTL1 24/4885KDM4E 2303/4885ATM 1493/4885
US-20180033975-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME SOD1, TELO2, L3MBTL4 L3MBTL1 14/4885KDM4E 2091/4885ATM 1846/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.