Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.35 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16349846 | 0.91 | PTGS2 (0.40) | PDE3BPDE3APTGS2PTGS1FEN1 | |
| SCHEMBL17615961 | 0.89 | PTGS2 (0.41) | PDE3BPDE3APTGS2PTGS1FEN1 | |
| SCHEMBL19229308 | 0.88 | ALOX5AP (0.43) | PDE3BPDE3APTGS2PTGS1ALOX5AP | |
| SCHEMBL172359 | 0.85 | PDE3B (0.47) | PDE3BPDE3APTGS2PTGS1ALOX5AP | |
| SCHEMBL15471663 | 0.84 | ALOX5AP (0.40) | PDE3BPDE3AALOX5APFEN1AKR1C3 | |
| SCHEMBL17356572 | 0.83 | AKR1C3 (0.44) | PDE3BPDE3APTGS2PTGS1ALOX5AP | |
| SCHEMBL16377230 | 0.82 | RARB (0.46) | ALOX5APFEN1S1PR1SMN1; SMN2DGAT1 | |
| SCHEMBL17356562 | 0.82 | AKR1C3 (0.40) | PDE3BPDE3APTGS2ALOX5APFEN1 | |
| SCHEMBL12735617 | 0.81 | FFAR4 (0.38) | PDE3BPDE3APTGS2PTGS1S1PR1 | |
| SCHEMBL18779780 | 0.81 | RARB (0.57) | S1PR1MAPTRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3159393-A1 | POLYMERIZABLE-MONOMER-CONTAINING LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DIC Corporation (JP) | 2017-04-26 | — | — | EP | disclosed |