Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.60 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.60 |
| ▸ | DPP9 | Q86TI2 | 10/20 | 0.60 |
| ▸ | FAP | Q12884 | 11/20 | 0.50 |
| ▸ | PREP | P48147 | 9/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 0.48 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780181 | 0.88 | DPP4 (0.53) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL15386478 | 0.86 | DPP4 (0.61) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL12658522 | 0.86 | DPP4 (0.61) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL18780158 | 0.86 | FAP (0.48) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL15386480 | 0.82 | DPP4 (0.67) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL13263364 | 0.82 | DPP4 (0.67) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL12658524 | 0.82 | DPP4 (0.67) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL15386477 | 0.82 | DPP4 (0.67) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL18780180 | 0.74 | DPP4 (0.50) | DPP4DPP8DPP9FAPPREP | |
| SCHEMBL19221502 | 0.73 | DPP4 (0.55) | DPP4DPP8DPP9FAPPREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629921-B2 | Smart pro-drugs of serine protease inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2017-04-25 | — | — | US | disclosed |