Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 16/20 | 0.50 |
| ▸ | FAP | Q12884 | 14/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.50 |
| ▸ | PREP | P48147 | 5/20 | 0.42 |
| ▸ | PITRM1 | Q5JRX3 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15386476 | 0.79 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13285457 | 0.79 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13263363 | 0.79 | DPP4 (0.58) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL18780174 | 0.75 | FAP (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL13285561 | 0.75 | FAP (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL18780179 | 0.74 | DPP4 (0.60) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL18780158 | 0.73 | FAP (0.48) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL18780181 | 0.69 | DPP4 (0.53) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL21746923 | 0.68 | DPP4 (1.00) | DPP4DPP7FAPDPP8DPP9 | |
| SCHEMBL8231049 | 0.68 | DPP4 (1.00) | DPP4DPP7FAPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9629921-B2 | Smart pro-drugs of serine protease inhibitors | TRUSTEES OF TUFTS COLLEGE (US) | 2017-04-25 | — | — | US | disclosed |