SCHEMBL18780293

SCHEMBL18780293

COC(C)COc1ccc(C(C)(C)c2ccc(O)c(C)c2)cc1C

nearest known ligand 0.54

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 17/20 0.54
RORC P51449 1/20 0.42
VDR P11473 2/20 0.41
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21469746 0.86 ESR1 (0.57) ESR1RORCVDRAR
SCHEMBL12573978 0.81 AR (0.62) ESR1VDRAR
SCHEMBL23054256 0.80 ESR1 (0.73) ESR1RORCAR
SCHEMBL18467873 0.78 ESR1 (0.71) ESR1AR
SCHEMBL30277599 0.75 VDR (0.44) VDRAR
SCHEMBL30365876 0.75 VDR (0.44) VDRAR
SCHEMBL18773664 0.74 ESR1 (0.78) ESR1VDR
SCHEMBL29350788 0.73 ESR1 (1.00) ESR1RORCAR
SCHEMBL29360146 0.73 ESR1 (1.00) ESR1RORCAR
SCHEMBL35285 0.73 ESR1 (1.00) ESR1RORCAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2633370-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KK (JP) 2017-04-26 EP disclosed