Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.40 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.39 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.39 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL1873956 | 0.90 | HRH3 (0.48) | HRH3 | |
| Trifluoroacetic Acid SCHEMBL1875279 | 0.87 | APAF1 (0.43) | KCNH2 | |
| Trifluoroacetic Acid SCHEMBL1875350 | 0.84 | MEN1 (0.41) | KDM4EALDH1A1HTTDRD4SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL1878150 | 0.84 | MEN1 (0.41) | KDM4EALDH1A1HTTDRD4SIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL1872782 | 0.83 | TNF (0.47) | KDM4EHPGDHRH3SMN1; SMN2POLB | |
| SCHEMBL12633994 | 0.81 | DRD4 (0.52) | KDM4EALDH1A1HPGDHTTCCNC | |
| Trifluoroacetic Acid SCHEMBL1877739 | 0.78 | OPRM1 (0.37) | CACNA1B | |
| SCHEMBL110226 | 0.77 | HRH3 (0.49) | KDM4EALDH1A1HPGDHTTCCNC | |
| Trifluoroacetic Acid SCHEMBL1875375 | 0.77 | KMT2A (0.49) | CACNA1B | |
| Trifluoroacetic Acid SCHEMBL1875954 | 0.75 | CACNA1B (0.42) | ALDH1A1HTTSMN1; SMN2CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939528-B2 | Heterocycle compounds | GLAXOSMITHKLINE LLC (US) | 2011-05-10 | — | — | US | disclosed |