Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 2/20 | 0.65 |
| ▸ | MMP2 | P08253 | 2/20 | 0.65 |
| ▸ | KDM1A | O60341 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.58 |
| ▸ | HTT | P42858 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684808 | 0.91 | MEN1 (0.65) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL685159 | 0.89 | NPC1 (0.70) | KDM1AMEN1KMT2ARAB9AMAPT | |
| SCHEMBL13549794 | 0.89 | KMT2A (0.69) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL14026534 | 0.88 | MAPT (0.67) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL685265 | 0.88 | KDM1A (0.65) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL13549782 | 0.88 | PSMD14 (0.64) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL684563 | 0.86 | KDM4E (0.65) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL14898605 | 0.85 | MAPT (0.65) | PSMD14MMP2KDM1AMEN1KMT2A | |
| SCHEMBL684648 | 0.85 | KDM1A (0.58) | PSMD14KDM1AMEN1KMT2ARAB9A | |
| SCHEMBL684660 | 0.85 | KDM1A (0.74) | KDM1AMEN1KMT2ARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9795610-B2 | Theramutein modulators | Housey, Gerard M. (US) | 2017-10-24 | — | — | US | disclosed |
| US-20170112848-A1 | THERAMUTEIN MODULATORS | HMI Medical Innovations, LLC | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170112848-A1 | THERAMUTEIN MODULATORS | TSG101, SERPINE1, PLAUR | PSMD14 935/4885MMP2 1978/4885KDM1A 4384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.