Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NOS2 | P35228 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780833 | 0.86 | TLR7 (0.42) | TLR7KDM4ENOS2MAPT | |
| SCHEMBL18781126 | 0.77 | TLR7 (0.41) | TLR7KDM4EKCNH2NOS2CNR1 | |
| SCHEMBL20406306 | 0.76 | PIK3CG (0.37) | TLR7KDM4ENOS2MAPT | |
| SCHEMBL7847399 | 0.73 | TLR7 (0.48) | TLR7KDM4ENOS2MAPT | |
| SCHEMBL18780955 | 0.72 | TLR7 (0.41) | TLR7KCNH2NOS2CNR1CNR2 | |
| SCHEMBL18780790 | 0.72 | MAPT (0.62) | TLR7KDM4ECNR1CNR2MAPT | |
| SCHEMBL18780788 | 0.71 | TLR7 (0.42) | TLR7KDM4ENOS2CNR2MAPT | |
| SCHEMBL18780811 | 0.71 | MAPT (0.47) | TLR7CNR1CNR2MAPT | |
| SCHEMBL14211728 | 0.71 | KDM4E (0.42) | KDM4EMAPT | |
| SCHEMBL11583625 | 0.70 | NOS2 (0.42) | TLR7KDM4EKCNH2NOS2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017069270-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |