Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.42 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18780955 | 0.86 | TLR7 (0.41) | TLR7NOS2MAPTCNR2ALOX5 | |
| SCHEMBL8568147 | 0.82 | NOS2 (0.41) | TLR7NOS2RAB9ANPC1KDM4E | |
| SCHEMBL18780833 | 0.82 | TLR7 (0.42) | TLR7NOS2RAB9ANPC1PIK3CG | |
| SCHEMBL18780790 | 0.76 | MAPT (0.62) | TLR7RAB9ANPC1MAPTCRHR1 | |
| SCHEMBL18780811 | 0.75 | MAPT (0.47) | TLR7RAB9ANPC1MAPTALDH1A1 | |
| SCHEMBL18781146 | 0.75 | PDE2A (0.39) | TLR7NOS2MAPTKDM4E | |
| SCHEMBL18780956 | 0.75 | NUDT1 (0.47) | TLR7RAB9ANPC1MAPTCRHR1 | |
| SCHEMBL544920 | 0.75 | RAB9A (0.45) | RAB9ANPC1PIK3CGMAPTALDH1A1 | |
| SCHEMBL18780810 | 0.74 | PDE2A (0.38) | TLR7MAPTCNR2KDM4E | |
| SCHEMBL18148772 | 0.74 | NPC1 (0.47) | RAB9ANPC1MAPTCKS1BSKP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017069270-A1 | NITROGEN-CONTAINING CONDENSED HETEROCYCLIC COMPOUND | 大正製薬株式会社 | 2017-04-27 | — | — | WO | disclosed |