Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 18/20 | 0.75 |
| ▸ | CASP7 | P55210 | 13/20 | 0.75 |
| ▸ | CASP1 | P29466 | 8/20 | 0.75 |
| ▸ | CASP4 | P49662 | 4/20 | 0.75 |
| ▸ | CASP9 | P55211 | 6/20 | 0.62 |
| ▸ | CASP10 | Q92851 | 4/20 | 0.58 |
| ▸ | CASP8 | Q14790 | 3/20 | 0.57 |
| ▸ | CASP5 | P51878 | 2/20 | 0.57 |
| ▸ | CASP2 | P42575 | 1/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19015962 | 1.00 | CASP3 (0.75) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL19015935 | 0.95 | CASP3 (0.69) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL19015922 | 0.89 | CASP3 (0.61) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL18782201 | 0.89 | CASP3 (0.61) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL19015955 | 0.87 | CASP3 (0.68) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL19015930 | 0.86 | CASP3 (0.78) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL7886294 | 0.86 | CASP3 (1.00) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL20052411 | 0.85 | CASP3 (0.66) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL18472720 | 0.85 | CASP3 (0.66) | CASP3CASP7CASP1CASP4CASP9 | |
| SCHEMBL18471954 | 0.85 | CASP3 (0.69) | CASP3CASP7CASP1CASP4CASP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10167313-B2 | Selective caspase inhibitors and uses thereof | GENESIS TECHNOLOGIES LIMITED (BB) | 2019-01-01 | — | — | US | disclosed |
| US-20170114092-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | GENESIS TECH LTD (BB) | 2017-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114092-A1 | SELECTIVE CASPASE INHIBITORS AND USES THEREOF | CASP1, CASP3, CASP5 | CASP3 2/4885CASP7 7/4885CASP1 1/4885 |
| US-10167313-B2 | Selective caspase inhibitors and uses thereof | CASP1, CASP3, CASP5 | CASP3 2/4885CASP7 7/4885CASP1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.